DESCRIPTION:

NEXGARD SPECTRA is a soft, beef-flavoured chewable tablet. Each chewable tablet contains the active ingredients, afoxolaner (an ectoparasiticide of the isoxazoline family) and milbemycin oxime (an endoparasiticide belonging to the group of macrocyclic lactones).

NexGard Spectra Chewable Tablets 9.4/1.9 mg (XS) Indications
NEXGARD SPECTRA chewable tablets are indicated in dogs and puppies 8 weeks of age or older for:

– the treatment and control of flea (Ctenocephalides felis) infestations and ticks,

– the treatment of demodicosis caused by Demodex canis,

– the prevention of heartworm disease (Dirofilaria immitis) (see CAUTIONS),

– the treatment and control of intestinal nematode infections caused by adult hookworms (Ancylostoma caninum), adult roundworms (Toxocara canis and Toxascaris leonina) and adult whipworms (Trichuris vulpis);

NEXGARD Spectra protects against adult Spirocerca lupi in the oesophagus in dogs and contains the active ingredients afoxolaner and milbemycin oxime.

Dosage and Administration
NEXGARD SPECTRA is given orally every 30 days, at the recommended dosage of 2.5 – 5 mg/kg of afoxolaner and 0.5 – 1 mg/kg of milbemycin oxime.

NEXGARD SPECTRA can be administered with or without food.

Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or rejected. If it is suspected that any of the dose has been lost, or vomiting occurs within 2 hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD SPECTRA and resume an every-30-day dosing regimen. To be effective NEXGARD SPECTRA should be administered every 30 days.

For prevention of flea infestation, NEXGARD SPECTRA should be administered ideally just before fleas become active. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.

Tick Treatment and Prevention:

Administration of NEXGARD SPECTRA should coincide with the time of year the ticks are active.

Treatment of Demodicosis:

NEXGARD SPECTRA should be administered monthly for 3 months. Skin scrapings should be done to assess the response to treatment. As demodicosis is a multi-factorial disease, where possible, it is advisable to also treat any underlying disease appropriately. Severe cases of generalized demodicosis may be difficult to cure.

Heartworm Prevention:

NEXGARD SPECTRA should be administered at monthly intervals beginning within 1 month of the dog’s first exposure to mosquitoes and continuing for 6 months after the dog’s last exposure to mosquitoes (see EFFICACY). To establish a treatment routine, it is recommended that the same day or date be used each month.

If treatment is delayed, whether by a few days or many, immediate treatment with NEXGARD SPECTRA and resumption of the recommended dosing regimen will minimize the opportunity for the development of adult heartworms.

Intestinal Nematodes Treatment and Prevention:

Dogs may be exposed to and can become infected with hookworms, roundworms and whipworms throughout the year.

CAUTIONS:

The safety of NEXGARD SPECTRA Chewable Tablets has not been evaluated in breeding, pregnant or lactating dogs. The safety of NEXGARD SPECTRA in puppies less than 8 weeks of age has not been evaluated.

Afoxolaner is a member of the isoxazoline class. This class has been associated with neurological adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurological disorders.

Storage
Store at room temperature between 15 – 30°C. Brief exposure (not to exceed 24 hours) up to 40°C is permitted. Keep the blister in the outer carton in order to protect from light.